Question 1

What is the median H-1B salary at Lyterian Therapeutics?

Accepted Answer

Lyterian Therapeutics pays a median H-1B salary of $145,180 for sponsored positions, with an average of $171,307. The average prevailing wage across Lyterian Therapeutics's filings is $120,632. These figures are based on Labor Condition Application filings with the Department of Labor.

Question 2

What is a prevailing wage determination?

Accepted Answer

A prevailing wage determination (PWD) is a wage rate set by the Department of Labor for a specific occupation and geographic area. Before filing an LCA, employers request a PWD from the DOL, which surveys wage data to determine what workers in similar roles are typically paid in that location. H-1B employers must pay at least the prevailing wage or the actual wage paid to other employees in the same role, whichever is higher. The prevailing wage column in the table above shows the DOL-determined floor for each position.

Question 3

How does Lyterian Therapeutics pay compared to the prevailing wage?

Accepted Answer

Lyterian Therapeutics's average offered wage is $171,307, compared to an average prevailing wage of $120,632 across its filings. When a company pays above the prevailing wage, it indicates the offered salary exceeds the DOL-determined market rate for the occupation and area. The salary table above shows both the offered and prevailing wages for each individual filing.

Question 4

What are H-1B wage levels I through IV?

Accepted Answer

The DOL sets prevailing wages at four levels: Level I (Entry) at the 17th percentile, Level II (Qualified) at the 34th percentile, Level III (Experienced) at the 50th percentile, and Level IV (Expert) at the 67th percentile. These levels reflect the complexity of the job duties and experience required. The prevailing wage is specific to each occupation (SOC code) and metropolitan statistical area. Higher wage levels indicate more senior positions.

Question 5

What is the H-1B salary requirement?

Accepted Answer

There is no single minimum salary for H-1B visas. Employers must pay the higher of the actual wage (what they pay other employees in the same role) or the prevailing wage determined by the DOL for the specific occupation and geographic area. The prevailing wage varies by job, location, and wage level. A Level I software engineer in a small metro area will have a very different floor than a Level IV software engineer in San Francisco or New York.

Job Title	Positions	Min	Median	Max
Executive Director, Early Lead Chemistry	2	$270,000	$275,400	$280,800
Scientist I	2	$130,000	$131,650	$133,300
Scientist Ii	1	$142,700	$142,700	$142,700
Senior Research Associate	1	$100,000	$100,000	$100,000
Senior Scientist	1	$166,000	$166,000	$166,000
Senior Scientist, Medicinal Chemistry	1	$147,659	$147,659	$147,659

Location	Positions	Min	Median	Max
South San Francisco, California	6	$100,000	$138,000	$280,800
S. San Francisco, California	1	$166,000	$166,000	$166,000
San Francisco, California	1	$270,000	$270,000	$270,000

Lyterian Therapeutics — H-1B Sponsored Salaries

Lyterian Therapeutics H1B Salaries

Salary by Job Title (2025)

Salary by Location (2025)

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